Join Arima ecDNA 3D Genomics Webinar: Unlock Cancer's Hidden Code
Thursday, November 20, 2025 - 18:00
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About the Webinar
This webinar will introduce ec3D, a pioneering computational method that harnesses Hi-C data to map the 3D structure of extrachromosomal DNA (ecDNA) in cancer, revealing how these circular DNA elements remodel genome architecture, activate oncogenes, and expose new therapeutic vulnerabilities unseen by traditional genomics.
What Will You Learn?
- Discover how the 3D organization of ecDNA rewires chromatin domains to enable enhancer hijacking, oncogene activation, and adaptive tumor evolution.
- Learn how ec3D reconstructs spatial ecDNA conformations from Hi-C data to uncover long-range genomic interactions linked to gene dysregulation and therapy resistance.
- Explore how this new 3D mapping framework could pave the way for precision therapies targeting the spatial organization of cancer genomes.
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