Decoding Gene Control: The Dual Power of Capture-C MPRA
Wednesday, May 28, 2025 | 18pm
About the Webinar
This webinar introduces Capture-C MPRA, a groundbreaking genomic technology that integrates 3D genome mapping with high-throughput functional assays to unravel the complex regulatory landscape of gene expression. Attendees will discover how this dual-purpose method links physical DNA interactions with regulatory activity, enabling precise mapping of enhancers and silencers to their target genes in a single experiment.
What You Will Learn:
- Discover how Capture-C MPRA combines promoter capture Hi-C and massively parallel reporter assays to simultaneously map promoter interactions and measure the regulatory activity of distal elements.
- Learn how this approach systematically identifies and assigns enhancers and silencers to specific genes, revealing new insights into enhancer-promoter specificity and the rules governing gene regulation.