miRNA Solutions from Abnova
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression and play essential
roles in various biological processes. Studying the distribution and localization of miRNAs within tissues or
cells is crucial for understanding their functional significance.
Abnova provides end-to-end solutions for miRNA isolation, reverse transcription for cDNA synthesis, quantification, and screening panels. Abnova reagents are manufactured under standardization and stringently quality controlled for research use.
One commonly used technique for visualizing miRNA expression patterns is miRNA in situ hybridization (miRNA ISH). This technique utilizes specific probes that hybridize with target miRNAs in biological samples such as formalin-fixed, paraffin-embedded (FFPE) tissues, freshly prepared frozen tissues or cultured cells, allowing for their detection and visualization. miRNA probes are typically with short nucleotide sequences and can be labeled with fluorescent or DIG tags for detection.
Applications of miRNA probes
- Gene regulation studies
- Functional analysis
- miRNA expression profiling
- Diagnostic biomarker discovery
- Drug discovery and development