Il prossimo incontro breve on-line
Wed, Aug 25, 2021 5:30 PM - 6:00 PM CEST
Genetex: Discovery of Novel Antiviral Agents Against Human Pathogenic Viruses: A Tale of Two Emerging Viruses – SARS-CoV-2 and Zika Virus
Dr. Jean’s research focuses on increasing our understanding of human viral diseases at the cellular level by identifying and studying the key viral and host cell enzymes essential for the viral life cycle(s), with subsequent discovery and development of enzyme inhibitors to interrupt these pathways. Dr. Jean will discuss his work with novel small-molecule inhibitors and protein-based therapeutics that function as direct- and indirect-acting antivirals against human pathogenic viruses of global public health concern, including SARS-CoV-2 and Zika virus. He will further explain the importance of his research findings for (i) generating effective tools for dissecting complex protease-activated pathways in vivo, (ii) defining the biological impact of new therapeutics on viral pathogenesis, and (iii) generating insights into new clinical approaches for treating important viral diseases caused by emerging human coronaviruses and flaviviruses.